Chromosome Addition and Subtraction
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Describes the polypoid nature of larval salivary cells of Drosophilia and certain human cells. Discusses non-disjunction as a mechanism for the addition and subtraction of single whole chromosomes, leading to haplo-IV and triplo-IV Drosophilia and to trisomics and monosomics in Datura. Compares tetraploids to tetrasomics. Explains the genetic basis of Mongolian idiocy. Discusses the consequences of a single break in a chromosome whose broken ends fail to join restitutionally. Lecture given by Dr. H. J. Muller.
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Original permalink · Record added 2024-04-22 15:14:30